Accuracy of ROPtool vs individual examiners in assessing retinal vascular tortuosity.
نویسندگان
چکیده
OBJECTIVE To prospectively determine if tortuosity assessment by a computer program (ROPtool) that traces retinal blood vessels and measures their tortuosity was more accurate than that of individual pediatric ophthalmologists. METHODS One hundred eighty-five high-quality RetCam images from premature infants were circulated to 3 retinopathy of prematurity (ROP) experts and 3 other pediatric ophthalmologists ("examiners") who graded the tortuosity in each quadrant as normal, pre-plus, or plus. These same images were analyzed using ROPtool. RESULTS Using expert consensus as the standard, ROPtool's overall accuracy of 95% (175 of 185) for identifying tortuosity sufficient for plus disease was similar to that of examiner 1 (93%; 172 of 185; P = .50), examiner 2 (93%; 172 of 185; P = .50), and examiner 3 (91%; 168 of 185; P = .10). ROPtool's sensitivity of 97% (36 of 37) compared favorably with that of examiner 1 (65%; 24 of 37; P < .001), examiner 2 (70%; 26 of 37; P < .001), and examiner 3 (81%; 30 of 37; P = .06). CONCLUSION Computer-assisted analysis of retinal images can potentially reduce subjectivity in the diagnosis of plus disease and optimize timing of follow-up and treatment for ROP.
منابع مشابه
Computer-assisted quantification of vascular tortuosity in retinopathy of prematurity (an American Ophthalmological Society thesis).
PURPOSE Plus disease is severely abnormal dilation and tortuosity of posterior retinal blood vessels in infants with retinopathy of prematurity (ROP). It has become the major criterion for laser treatment in ROP, but its assessment is subjective and prone to error. ROPtool is a computer program that traces retinal blood vessels, measures their tortuosity, and determines whether there is suffici...
متن کاملComputer-assisted measurement of retinal vascular width and tortuosity in retinopathy of prematurity.
OBJECTIVES To validate the accuracy of ROPtool software in measuring retinal vascular width and tortuosity in a large image set compared with expert diagnoses. METHODS Tortuosity and dilation indexes generated by ROPtool were compared with 3 expert consensus grades of normal, pre-plus, or plus disease for 368 quadrants in 92 RetCam (Clarity Medical Systems, Pleasanton, California) fundus imag...
متن کاملUsing an Image Fusion Methodology to Improve Efficiency and Traceability of Posterior Pole Vessel Analysis by ROPtool
BACKGROUND The diagnosis of plus disease in retinopathy of prematurity (ROP) largely determines the need for treatment; however, this diagnosis is subjective. To make the diagnosis of plus disease more objective, semi-automated computer programs (e.g. ROPtool) have been created to quantify vascular dilation and tortuosity. ROPtool can accurately analyze blood vessels only in images with very go...
متن کاملMeasurement and classi cation of retinal vascular tortuosity
Automatic measurement of blood vessel tortuosity is a useful capability for automatic ophthal-mological diagnostic tools. We describe a suite of automated tortuosity measures for blood vessel segments extracted from RGB retinal images. The tortuosity measures were evaluated in two classii-cation tasks: (1) classifying the tortuosity of blood vessel segments and (2) classifying the tortuosity of...
متن کاملA prospective case-control study to investigate retinal microvascular changes in acute dengue infection.
Dengue infection can affect the microcirculation by direct viral infection or activation of inflammation. We aimed to determine whether measured retinal vascular parameters were associated with acute dengue infection. Patients with acute dengue were recruited from Communicable Diseases Center, Singapore and age-gender-ethnicity matched healthy controls were selected from a population-based stud...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Archives of ophthalmology
دوره 125 11 شماره
صفحات -
تاریخ انتشار 2007